- D.A. Low, M. Nystrom, E. Kalinin, P. Parikh, J.F. Dempsey, J.D. Bradley, S. Mutic, S.H. Wahab, T. Islam, G. Christensen, D.G. Politte, and B.R. Whiting, A method for the reconstruction of 4-dimensional synchronized CT scans acquired during free breathing, Med. Phys.30, 1254-1263 (2003).
- D. A. Low, P. J. Parikh, W. Lu, J. F. Dempsey, S. H. Wahab, J. P. Hubenschmidt, M. M. Nystrom, M. Handoko, and J. D. Bradley, A novel breathing motion model for radiation therapy, Int. J. Radiat. Oncol. Biol. Phys. 63, 921-929 (2005).
- D.A. Low, B. White, P. Lee, D. Thomas, S. Gaudio, S. Jani, X. Wu, and J. Lamb, A novel CT acquisition and analysis technique for breathing motion modeling, Phys. Med. and Biol. 58, L31-L36 (2013).
- D. Thomas, J. Lamb, B. White, S. Jani, S. Gaudio, P. Lee, D. Ruan, M. McNitt-Gray, and D.A. Low, A novel fast-helical 4D-CT acquisition technique to generate low noise artifact-free images at user selected breathing phases, Int. J. Radiat. Oncol., Biol., Phys. 89 191-198 (2014).
- T. Dou, D. Thomas, D. O’Connell, J. Lamb, P. Lee, and D.A. Low, A method for assessing ground-truth accuracy of the 5DCT technique, Int. J. Radiat. Oncol. Biol. Phys, 93, 925-933 (2015).
Evidence
Articles, Research, Journals, References, Papers
- D.A. Low, T. Zhao, B. White. D. Yang, S. Mutic, C. Noel, J. Bradley, P. Parikh, and W. Lu, Application of the continuity equation to a breathing motion model, Med. Phys. 37, 1360-1364 (2010).
- T. Zhao, B. White, K. Moore, J. Lamb, D. Yang, W. Lu, S. Mutic, and D.A. Low, Biomechanical interpretation of a free-breathing lung motion model, Phys. Med. Biol. 56, 7523-7540 (2011).
- D. O’Connell, D. Thomas, T. Dou, J. Lamb, F. Feingold, M. Fuld, C. Hofmann, M. Shirk, C. Sloan, J. Sieren, E. Hoffman, and D.A. Low, Comparison of breathing gated CT images generated using a 5DCT technique and a commercial clinical protocol in a porcine model, Med. Phys. 42, 4033-4042 (2015).
- D. O’Connell, D. Thomas, J. Lamb, J. Lewis, T. Dou, J. Sieren, M. Saylor, C. Hofmann, E. Hoffman, P. Lee, and D.A. Low, Dependence of subject-specific parameters for a fast helical CT respiratory motion model on breathing rate: an animal study, Physics in Medicine and Biology 63, 8pp (2018).
- D. O’Connell, N. Shaverdian, A. Kishan, D. Thomas, T. Dou, J. Lewis, J. Lamb, M. Cao, S. Tenn, P. Lee, and D.A. Low, Comparison of lung tumor motion measured using a model-based 4DCT technique and a commercial protocol, Practical Radiation Oncology 8, E175-E183 (2018).
- J. Liu, X. Zhang, X. Zhang, H. Zhao, Y. Gao, D. Thomas, D.A. Low, and H.Gao, 5D respiratory model based image reconstruction algorithm for 4D cone- beam computed tomography, Inverse Problems 31, 115007, 21pp (2015).
- G. Chee, D. O’Connell, Y. Yang, K. Singhrao, D.A. Low, and J. Lewis, McSART: An iterative model-based, motion-compensated SART algorithm for CBCT reconstruction, Phys. Med. Biol. 64, 095013 (2019).
- M. Guo, G. Chee, D. O'Connell, S. Dhou, J. Fu, K. Singhrao, D. Ionascu, D. Ruan, P. Lee, D.A. Low, J. Zhao, and J. Lewis, Reconstruction of a high- quality volumetric image and a respiratory motion model from patient CBCT
projections, Med. Phys. 46 3627-3639 (2019). - M. Lauria, C. Miller, K. Singhrao, J. Lewis, W. Lin, D. O’Connell, L. Naumann , B. Stiehl, A. Santhanam, P. Boyle, A. Raldow, J. Goldin, I. Barjaktarevic and D. A. Low, Motion compensated cone-beam CT reconstruction using an a priori motion model from CT simulation: a pilot study, Phys. Med. Biol. 69, 19pp (2024).
- D. O’Connell, D. Thomas, J. Lewis, K. Hasse, A. Santhanam, J. Lamb, M. Cao, S. Tenn, N. Agazaryan, P. Lee and D.A. Low, Safety-oriented design of in-house software for new techniques: A case study using a model-based 4DCT protocol, Med. Phys. 46, 1523-1532 (2019).
- M. Lauria, M. Kim, D. O'Connell, Y. Lao, C. Miller, L. Naumann, P. Boyle,A. Raldow, A. Lee, R. Savjani, D. Moghanaki, and D. A. Low, A Retrospective Analysis of the First Clinical 5DCT Workflow, Accepted for publication, Cancers, February 2025.
- W. Lu, D.A. Low, P. J. Parikh, M. M. Nystrom, I. M. ElNaqa, S. H. Wahab, M. Handoko, D. Fooshee, and J. D. Bradley, Comparison of spirometry and abdominal height as four-dimensional computed tomography metrics in lung, Med. Phys. 32, 2351-2357 (2005).
- T. Zhao, W. Lu, D. Yang, S. Mutic, C. Noel, P. Parikh, J. Bradley, and D.A. Low, Characterization of free breathing patterns with 5D lung motion model, Med. Phys. 36, 5183-5189 (2009).
- R. Werner, B. White, H. Handels, W. Lu, and D.A. Low, Development of a tidal volume surrogate that replaces spirometry for physiologic breathing monitoring in 4D CT, Med. Phys. 37, 615-619 (2010).
- B. White, D.A. Low, T. Zhao, W. Wuenschel, W. Lu, J. Lamb, S. Mutic, J. Bradley, and I. El Naqa, Investigation of a breathing surrogate prediction algorithm for prospective pulmonary gating, Med. Phys. 38, 1587-1595 (2011).
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B. White, T. Zhao, J. Lamb, S. Wuenschel, J. Bradley, I. El Naqa, and D.A. Low, Distribution of lung tissue hysteresis during free breathing, Med. Phy. 40, 043501-1-043501-8 (2013).
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B. White, T. Zhao, J. Lamb, J. Bradley, and D.A. Low, Quantification of the thorax-to-abdomen breathing ratio for breathing motion modeling, Med. Phys. 40, 063502-1 to 063502-5 (2013).
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B. White, T. Zhao, J. Lamb, J. Bradley, and D.A. Low, Technical Note: Physiologically guided approach to characterizing respiratory motion, Med. Phys. 40, 121723-1 to 121723-6 (2013).
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B. White, A. Santhanam, D. Thomas, Y, Min, J. Lamb, J. Neylon, S. Jani, S. Gaudio, S. Srinivasan, D. Ennis, and D.A. Low, Modeling and incorporating cardiac-induced lung tissue motion in a breathing motion model, Med. Phys. 42,043501-1-043501-11 (2014).
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D. Ruan, D. Thomas, and D.A. Low, Objective function to obtain multiple representative waveforms for a novel helical CT scan protocol, Med. Phys. 42, 1164-1169 (2015).
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T. Dou, D. Thomas, D. O’Connell, J. Bradley, J. Lamb, and D.A. Low, Technical Note: Simulation of 4DCT tumor motion measurement errors, Med. Phys. 42, 6084-6089 (2015).
20. J. Kiely, A. Olszanski, S. Both, D.A. Low, and B. White, Quantitative early decision making metric for identifying irregular breathing in 4DCT, Med. Phys. 42, 5654-5660 (2015). -
D. Thomas, D. Ruan, P. Williams, J. Lamb, B. White, T. Dou, D. O’Connell, P. Lee, and D.A. Low, Is there an ideal set of prospective scan acquisition phases for fast-helical based 4D-CT?, Phys. Med. Biol. 61, N632-N641 (2016).
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D. O’Connell, D. Ruan, D. Thomas, T. Dou, J. Lewis, A. Santhanam, P. Lee, and D.A. Low, A prospective gating method to acquire a diverse set of free-breathing CT images for model-based 4DCT, Phys. Med. Biol. 63, 10
pages (2018). -
P. Boyle, L. Naumann, M. Lauria, C. Miller, R. Andosca, R. Savjani, D. O’Connell, D. Moghanaki, I. Barjaktarevic, J. Goldin, and D. A. Low, Introducing a novel sub-millimeter lung CT image registration error quantitation tool. Medical Physics (In Press), November 2024.
- K. Hasse, D. O’Connell, Y. Min, J. Neylon, D.A. Low, and A. Santhanam, Estimation and validation of patient-specific high-resolution lung elasticity derived from 4DCT, Med. Phys. 45, 666-677 (2018).
- J. McClelland, M. Modat, S. Arridge, H. Grimes, D. D’Souza, D. Thomas, D. O’Connell, D.A. Low, E. Kaza, D. Collins, M. Leach, and D. Hawkes, A generalized framework unifying image registration and respiratory motion models and incorporating image reconstruction, for partial image data or full images, Phys. Med. Biol. 62, 4273-4292 (2017).
- B. Stiehl, M. Lauria, D. O’Connell, K. Hasse, I. Barjaktarevic, P. Lee, D.A. Low, and A. Santhanam, A quantitative analysis of biomechanical lung model consistency using 5DCT datasets, Med. Phys. 47, 5555-5567 (2020).
- D.A. Low, D. O’Connell, M. Lauria, B. Stiehl, L. Naumann, P. Lee, J. Hegde, I. Barjaktarevic, J. Goldin, and A. Santhanam, Ventilation Measurements Using Fast-Helical Free-Breathing CT, Med. Phys. 48, 6094-6105 (2021).
- M. Lauria. B. Stiehl, A. Santhanam, D. O'Connell, L. Naumann, M. McNitt- Gray, A. Raldow, J. Goldin, I. Barjaktarevic, and D.A. Low, An Analysis of the Regional Heterogeneity in Tissue Elasticity in Lung Cancer Patients with COPD, Frontiers in Medicine-Pulmonary Medicine 10, 10pp (2023).
- G. Valdes, C. Lee, S. Tenn, P. Lee, C. Robinson, K. Iwamoto, D.A. Low, and J. Lamb, The relative accuracy of 4D dose accumulation for lung radiotherapy using rigid dose projection versus dose recalculation on every breathing phase, Med. Phys 44, 1120-1127 (2017).
- D.A. Low, L. Yang, J. Chen, D. O’Connell, J. Lewis, D. Thomas, and P. Lee, Technical Note: Analysis of motion blurring artifact in fast helical free breathing thoracic CT scans, Med. Phys. 44, 1456-1461 (2017).
- D. Thomas, J. Tan, J. Neylon, T. Dou, D. O’Connell, M. McNitt-Gray, P. Lee, J. Lamb, and D.A. Low, Investigating the minimum scan parameters required to generate free-breathing motion artefact-free fast-helical CT, Br. J. Radiol. 91 (2018).
- M. Lauria, R. Navaratna, D. O’Connell, A. Santhanam, and D.A. Low, Technical Note: Investigating internal-external motion correlation using fast helical CT, Med. Phys. 48, 1823-1831 (2021).