Evidence

Articles, Research, Journals, References, Papers

  1. D.A.Low, M. Nystrom, E. Kalinin, P. Parikh, J.F. Dempsey, J.D. Bradley, S. Mutic, S.H. Wahab, T. Islam, G. Christensen, D.G. Politte, and B.R. Whiting, A method for the reconstruction of 4-dimensional synchronized CT scans acquired during free breathing, Med. Phys.30, 1254-1263 (2003).
  2. Lu, P. Parikh, I. ElNaqa, M. Nystrom, J. Hubenschmidt, S. Wahab, S. Mutic, A. Sing, G. Christensen, J.D. Bradley, and D.A. Low, Quantitation of the reconstruction quality of a four-dimensional computed tomography process for lung cancer patients, Med. Phys. 32, 890-901 (2005).
  3. Lu, D.A. Low, P. J. Parikh, M. M. Nystrom, I. M. ElNaqa, S. H. Wahab, M. Handoko, D. Fooshee, and J. D. Bradley, Comparison of spirometry and abdominal height as four-dimensional computed tomography metrics in lung, Med. Phys. 32, 2351-2357 (2005).
  4. D.A.Low, P. J. Parikh, W. Lu, J. F. Dempsey, S. H. Wahab, J. P. Hubenschmidt, M. M. Nystrom, M. Handoko, and J. D. Bradley, A novel breathing motion model for radiation therapy, Int. J. Radiat. Oncol. Biol. Phys. 63, 921-929 (2005).
  5. A. Simon, G.E. Christensen, D.A. Low, and J.M. Reinhardt, Computed tomography studies of lung mechanics, Proceedings of the American Thoracic Society, 2, 517-521, 506-507 (2005).
  6. Lu, P.J. Parikh, J.P. Hubenschmidt, D.G. Politte, B.R. Whiting, J.D. Bradley, S. Mutic, and D.A. Low, Reduction of motion blurring artifacts using respiratory gated CT in sinogram space: A quantitative evaluation, Med. Phys. 32, 3295-3304 (2005).
  7. Lu, P.J. Parikh, J.P. Hubenschmidt, J.D. Bradley, and D.A. Low, A comparison between amplitude sorting and phase-angle sorting using external respiratory measurement for 4D CT, Med. Phys. 33, 2964-2974 (2006).
  8. El Naqa, D.A. Low, J.D. Bradley, M. Vicic, and J.O. Deasy, Deblurring of breathing motion artifacts in thoracic PET images by deconvolution, Med. Phys. 33, 3587-3600 (2006).
  9. D. Bradley, A.N. Nofal, I. El Naqa, W. Lu, J. Liu, J. Hubenschmidt, D.A. Low, R.E. Drzymala, D. Khullar, Comparison of helical, maximum intensity projection (MIP), and averaged intensity (AI) 4D CT imaging for stereotactic body radiation therapy (SBRT) planning in lung cancer, Radiother. Oncol. 81, 264-268 (2006).
  10. Lu, M.M. Nystrom, P.J. Parikh, D.R. Fooshee, J.P. Hubenshmidt, J.D. Bradley, and D.A. Low, A semi-automatic method for peak and valley detection in free-breathing respiratory waveforms, Med. Phys. 33, 3634-3636 (2006).
  11. Handels, R. Werner, T. Frenzel, D. Saring, W. Lu, D.A. Low and J. Erhardt, Generation of 4D CT image data and analysis of lung tumour mobility during the breathing cycle, Stud. Health. Technol. Inform. 124, 977-982 (2006).
  12. Erhardt, R. Werner, D. Säring, T. Frenzel, W. Lu, D.A. Low, and H. Handels, An optical flow based method for improved reconstruction of 4D CT data sets acquired during free breathing, Medical Physics 34, 711-721 (2007).
  13. E. Christensen, J.H. Song, W. Lu., I. El Naqa, and D.A. Low, Tracking Lung Motion with Inverse Consistent Image Registration. Med. Phys. 34, 2155-2163 (2007).
  14. Werner, H. Handels, J. Erhardt, D. Saring, T. Frenzel, W. Lu, and D.A. Low, Motion artifact reducing reconstruction of 4D CT image data for the analysis of respiratory dynamics, Methods Inf Med 46, 254-260 (2007).
  15. Handels, R. Werner, R. Schmidt, T. Frenzel, W. Lu, D.A. Low, and J. Ehrhardt, 4D medical image computing and visualization of lung tumor mobility in spatio-temporal CT image data, Int. J. Medical Informatics 76S, S433-S439 (2007).
  16. R. Olsen, W. Lu, J. P. Hubenschmidt, M. M. Nystrom, P. Klahr, J.D. Bradley, D.A. Low, and P. Parikh, Effect of a novel amplitude/phase binning algorithm on commercial 4DCT quality, Int. J. Radiat. Oncol. Biol. Phys. 70, 243-252 (2008).
  17. Yang, W. Lu, D.A. Low, J.O. Deasy, A. J. Hope, and I. El Naqa, 4D-CT motion estimation using deformable image registration and 5D respiratory motion modeling, Med. Phys. 35, 4577-4590 (2008).
  18. Li, H. Xie, H. Ning, W. Lu, D.A. Low, D. Citrin, A. Kaushal, L. Zach, K. Camphausen, and R. Miller, A novel analytical approach to prediction of respiratory diaphragm motion based on external torso volume change, Phys. Med. Biol. 54, 4113-4130 (2009).
  19. Zhao, W. Lu, D. Yang, S. Mutic, C. Noel, P. Parikh, J. Bradley, and D.A. Low, Characterization of free breathing patterns with 5D lung motion model, Med. Phys. 36, 5183-5189 (2009).
  20. Werner, B. White, H. Handels, W. Lu, and D.A. Low, Development of a tidal volume surrogate that replaces spirometry for physiologic breathing monitoring in 4D CT, Med. Phys. 37, 615-619 (2010).
  21. A. Low, T. Zhao, B. White. D. Yang, S. Mutic, C. Noel, J. Bradley, P. Parikh, and W. Lu, Application of the continuity equation to a breathing motion model, Med. Phys. 37, 1360-1364 (2010).
  22. White, D.A. Low, T. Zhao, W. Wuenschel, W. Lu, J. Lamb, S. Mutic, J. Bradley, and I. El Naqa, Investigation of a breathing surrogate prediction algorithm for prospective pulmonary gating, Med. Phys. 38, 1587-1595 (2011).
  23. Li, J. Lewis, X. Jia, T. Zhao, W. Liu, J. Lamb, D Yang, D.A. Low, S. Jiang, On a PCA-based lung motion model, Phys Med Biol. 56, 6009-6030 (2011).
  24. Zhao, B. White, K. Moore, J. Lamb, D. Yang, W. Lu, S. Mutic, and D.A. Low, Biomechanical interpretation of a free-breathing lung motion model, Phys. Med. Biol. 56, 7523-7540 (2011).
  25. Smith, D. Yang, A. Lee, M. Mayse, D.A. Low, and P. Parikh, The correlation of tissue motion within the lung: implications on fiducial based treatments, Med. Phys. 38, 5992-5997 (2011).
  26. A. Low, 4D imaging and 4D radiation therapy: a new era of therapy design and delivery, Front Radiat Ther Oncol 43, 99-117 (2011).
  27. Li, C. Noel, J. Garcia-Ramirez, D.A. Low, J. Bradley, C. Robinson, S. Mutic, and P. Parikh, Clinical evaluations of an amplitude-based binning algorithm for 4DCT reconstruction in radiation therapy, Med. Phys. 39, 922-932 (2012).
  28. Hu, S. Caruthers, D.A. Low, P. Parikh, and S. Mutic, Respiratory Amplitude Guided 4D Magnetic Resonance Imaging, Int. J. Radiat. Oncol. Biol. Phys. 86, 198-204 (2013).
  29. White, T. Zhao, J. Lamb, S. Wuenschel, J. Bradley, I. El Naqa, and D.A. Low, Distribution of lung tissue hysteresis during free breathing, Med. Phy. 40, 043501-1-043501-8 (2013).
  30. D.A.Low, B. White, P. Lee, D. Thomas, S. Gaudio, S. Jani, X. Wu, and J. Lamb, A novel CT acquisition and analysis technique for breathing motion modeling, Phys. Med. and Biol. 58, L31-L36 (2013).
  31. White, T. Zhao, J. Lamb, J. Bradley, and D.A. Low, Quantification of the thorax-to-abdomen breathing ratio for breathing motion modeling, Med. Phys. 40, 063502-1 to 063502-5 (2013).
  32. White, T. Zhao, J. Lamb, J. Bradley, and D.A. Low, Technical Note: Physiologically guided approach to characterizing respiratory motion, Med. Phys. 40, 121723-1 to 121723-6 (2013).
  33. Thomas, J. Lamb, B. White, S. Jani, S. Gaudio, P. Lee, D. Ruan, M. McNitt-Gray, and D.A. Low, A novel fast-helical 4D-CT acquisition technique to generate low noise artifact-free images at user selected breathing phases, Int. J. Radiat. Oncol., Biol., Phys. 89 191-198 (2014).
  34. White, A. Santhanam, D. Thomas, Y, Min, J. Lamb, J. Neylon, S. Jani, S. Gaudio, S. Srinivasan, D. Ennis, and D.A. Low, Modeling and incorporating cardiac-induced lung tissue motion in a breathing motion model, Med. Phys. 41, 043501-1-043501-11 (2014).
  35. Ruan, D. Thomas, and D.A. Low, Objective function to obtain multiple representative waveforms for a novel helical CT scan protocol, Med. Phys. 42, 1164-1169 (2015).
  36. White, S. Vennarini, L. Lin, G. Freedman, A. Santhanam, D.A. Low and S. Both, Accuracy of routine treatment planning 4D and DIBH CT delineation of the left anterior descending artery in radiotherapy, Int. J. Radiat. Oncol. Biol. Phys. 91, 825-831 (2015).
  37. O’Connell, D. Thomas, T. Dou, J. Lamb, F. Feingold, M. Fuld, C. Hofmann, M. Shirk, C. Sloan, J. Sieren, E. Hoffman, and D.A. Low, Comparison of breathing gated CT images generated using a 5DCT technique and a commercial clinical protocol in a porcine model, Med. Phys. 42, 4033-4042 (2015).
  38. Dou, D. Thomas, D. O’Connell, J. Lamb, P. Lee, and D.A. Low, A method for assessing ground-truth accuracy of the 5DCT technique, Int. J. Radiat. Oncol. Biol. Phys, 93, 925-933 (2015).
  39. Dou, D. Thomas, D. O’Connell, J. Bradley, J. Lamb, and D.A. Low, Technical Note: Simulation of 4DCT tumor motion measurement errors, Med. Phys. 42, 6084-6089 (2015).
  40. Liu, X. Zhang, X. Zhang, H. Zhao, Y. Gao, D. Thomas, D.A. Low, and H. Gao, 5D respiratory model based image reconstruction algorithm for 4D cone-beam computed tomography, Inverse Problems 31, 115007, 21pp (2015).
  41. Kiely, A. Olszanski, S. Both, D.A. Low, and B. White, Quantitative early decision making metric for identifying irregular breathing in 4DCT, Med. Phys. 42, 5654-5660 (2015).
  42. Thomas, D. Ruan, P. Williams, J. Lamb, B. White, T. Dou, D. O’Connell, P. Lee, and D.A. Low, Is there an ideal set of prospective scan acquisition phases for fast-helical based 4D-CT?, Phys. Med. Biol. 61, N632-N641 (2016).
  43. Valdes, C. Lee, S. Tenn, P. Lee, C. Robinson, K. Iwamoto, D.A. Low, and J. Lamb, The relative accuracy of 4D dose accumulation for lung radiotherapy using rigid dose projection versus dose recalculation on every breathing phase, Med. Phys 44, 1120-1127 (2017).
  44. D.A.Low, L. Yang, J. Chen, D. O’Connell, J. Lewis, D. Thomas, and P. Lee, Technical Note: Analysis of motion blurring artifact in fast helical free breathing thoracic CT scans, Med. Phys. 44, 1456-1461 (2017).
  45. Hasse, D. O’Connell, Y. Min, J. Neylon, D.A. Low, and A. Santhanam, Estimation and validation of patient-specific high-resolution lung elasticity derived from 4DCT, Med. Phys. 45, 666-677 (2018).
  46. O’Connell, D. Ruan, D. Thomas, T. Dou, J. Lewis, A. Santhanam, P. Lee, and D.A. Low, A prospective gating method to acquire a diverse set of free-breathing CT images for model-based 4DCT, Phys. Med. Biol. 63, 10 pages (2018).
  47. O’Connell, D. Thomas, J. Lamb, J. Lewis, T. Dou, J. Sieren, M. Saylor, C. Hofmann, E. Hoffman, P. Lee, and D.A. Low, Dependence of subject-specific parameters for a fast helical CT respiratory motion model on breathing rate: an animal study, Physics in Medicine and Biology 63, 8pp (2018).
  48. McClelland, M. Modat, S. Arridge, H. Grimes, D. D’Souza, D. Thomas, D. O’Connell, D.A. Low, E. Kaza, D. Collins, M. Leach, and D. Hawkes, A generalized framework unifying image registration and respiratory motion models and incorporating image reconstruction, for partial image data or full images, Phys. Med. Biol. 62, 4273-4292 (2017).
  49. Thomas, J. Tan, J. Neylon, T. Dou, D. O’Connell, M. McNitt-Gray, P. Lee, J. Lamb, and D.A. Low, Investigating the minimum scan parameters required to generate free-breathing motion artefact-free fast-helical CT, Br. J. Radiol. 91 (2018).
  50. Han, Z. Zhou, D. Du, Y. Gao, S. Rashid, M. Cao, N. Shaverdian, J. Hegde, M. Steinberg, P. Lee, A. Raldow, D.A. Low, K. Sheng, Y. Yang, and P. Hu, Respiratory motion-resolved, self-gated 4D-MRI using rotating Cartesian K-Space (ROCK): Initial clinical experience on an MRI-guided radiotherapy system, Radiother. and Oncol 127, 467-473 (2018).
  51. O’Connell, N. Shaverdian, A. Kishan, D. Thomas, T. Dou, J. Lewis, J. Lamb, M. Cao, S. Tenn, P. Lee, and D.A. Low, Comparison of lung tumor motion measured using a model-based 4DCT technique and a commercial protocol, Practical Radiation Oncology 8, E175-E183 (2018).
  52. Chee, D. O’Connell, Y. Yang, K. Singhrao, D.A. Low, and J. Lewis, McSART: An iterative model-based, motion-compensated SART algorithm for CBCT reconstruction, Phys. Med. Biol. 64, 095013 (2019).
  53. O’Connell, D. Thomas, J. Lewis, K. Hasse, A. Santhanam, J. Lamb, M. Cao, S. Tenn, N. Agazaryan, P. Lee and D.A. Low, Safety-oriented design of in-house software for new techniques: A case study using a model-based 4DCT protocol, Med. Phys. 46, 1523-1532 (2019).
  54. Ginn, D. Ruan, D.A. Low, and J. Lamb, Image regression technique for motion prediction in MRI-guided radiotherapy, Med. Phys. 47, 404-413 (2019).
  55. Guo, G. Chee, D. O’Connell, S. Dhou, J. Fu, K. Singhrao, D. Ionascu, D. Ruan, P. Lee, D.A. Low, J. Zhao, and J. Lewis, Reconstruction of a high-quality volumetric image and a respiratory motion model from patient CBCT projections, Med. Phys. 46 3627-3639 (2019).
  56. Stiehl, M. Lauria, D. O’Connell, K. Hasse, I. Barjaktarevic, P. Lee, D.A. Low, and A. Santhanam, A quantitative analysis of biomechanical lung model consistency using 5DCT datasets, Med. Phys. 47, 5555-5567 (2020).
  57. Lauria, R. Navaratna, D. O’Connell, A. Santhanam, and D.A. Low, Technical Note: Investigating internal-external motion correlation using fast helical CT, Med. Phys. 48, 1823-1831 (2021).
  58. D.A.Low, D. O’Connell, M. Lauria, B. Stiehl, L. Naumann, P. Lee, J. Hegde, I. Barjaktarevic, J. Goldin, and A. Santhanam, Ventilation Measurements Using Fast-Helical Free-Breathing CT, Accepted for publication, Medical Physics, July 2021.